Tuam txhab Profile
Guangzhou G-Cell Technology Co., Ltd. yog lub tuam txhab thev naus laus zis tshiab tsim los ntawm kev cia siab rau Tsinghua University Shenzhen Kawm Tiav Tsev Kawm Ntawv, Southern University of Science thiab Technology, thiab South China Normal University, thiab peb tsom mus rau daim ntawv thov ntawm optical imaging technology nyob rau hauv lub teb ntawm life sciences. Rau cov chav nyob hauv cov lus qhia txog kev thov, peb tuaj yeem muab koj cov khoom siv kho qhov muag pom kev thiab cov kev daws teeb meem. Peb muaj qhov ua tiav kev sim kho qhov muag qhov chaw sim thiab ib pawg ntawm cov tub ntxhais hluas cov pob txha zoo. Raws li kev sib koom ua ke ntawm cov khoom siv hauv chav kuaj thiab kev lag luam hauv Is Taws Nem, lub tuam txhab tau cog lus los tsim lub cim tshiab ntawm cov khoom siv ntse ntse.
Vim Li Cas Xaiv Peb
Pab neeg ua haujlwm
Peb tshwj xeeb hauv kev siv thev naus laus zis kho qhov muag rau thaj tsam ntawm cell biology. Rau kev tshawb fawb ntawm tes, kev soj ntsuam thiab lwm daim ntawv thov teb.Peb muaj qhov ua tiav kev sim kho qhov muag sim platform thiab ib pawg ntawm cov tub ntxhais hluas cov pob txha zoo tshaj plaws.
Cov cuab yeej siv siab heev
Raws li kev sib koom ua ke ntawm cov khoom siv hauv chav kuaj thiab kev lag luam hauv Is Taws Nem, lub tuam txhab tau cog lus los tsim lub cim tshiab ntawm cov khoom siv ntse ntse.
Kev tshawb fawb ywj pheej thiab kev txhim kho
Raws li kev tsim kho tshiab ntawm pab pawg tshawb fawb thiab kev txhim kho muaj zog, GCell cov khoom lag luam tau txais kev ywj pheej tshawb fawb thiab kev tsim kho, kev tsim khoom ywj pheej, kev ywj pheej patents, thiab tau dhau ntau daim ntawv pov thawj xws li software monographs thiab cov qauv siv hluav taws xob patents.
Software zoo
Software tuning yog ua raws li kev siv tus cwj pwm ntawm cov neeg siv tshawb fawb tshawb fawb, thiab cov txiaj ntsig tau raug xa tawm raws li qhov xav tau ntawm cov ntawv tshawb fawb tshawb fawb thiab cov ntawv ceeb toom. Daim ntawv saib ua ntej cov ntaub ntawv tuaj yeem muab rov qab tau txhua lub sijhawm, thiab txhawb kev hloov pauv ntawm cov txiaj ntsig panoramic, uas yooj yim rau kev tshawb fawb thoob ntiaj teb.
Tsiaj Cwj Pwm Analysis suav nrog
High Resolution Gait Analysis System
Dab tsi yog High Resolution Gait Analysis System
Qhov sib txawv ntawm kev daws teeb meem gait tsom xam qhov sib txawv tuaj yeem muab faib ua kev soj ntsuam thiab ntau. Observational siab daws teeb meem gait tsom xam cov ntaub ntawv gleaned los ntawm kev soj ntsuam tus neeg mob; quantitative gait analysis yog cov ntaub ntawv sau hauv tshuab hluav taws xob. Raws li kev daws teeb meem gait tsom xam qhov system tuaj yeem qhia tau tias muaj teeb meem kev noj qab haus huv, txheeb xyuas thiab daws qhov txawv txav thiab asymmetries yog qhov tseem ceeb tshaj plaws.
Qhov zoo ntawm High Resolution Gait Analysis System
Real-time wireless kis tau tus mob
Siv li ntawm 10 meters, thiab tso saib tus neeg siv lub cev qis qis ntawm lub vijtsam hauv lub sijhawm.
Gait cov ntaub ntawv kaw
Sau cov ntaub ntawv nyob rau hauv lub software los pab kom replay thiab tsom xam ntawm tus neeg siv gait txhua lub sij hawm.
Tshaj tawm kev cai ua haujlwm
Daim ntawv tshaj tawm tuaj yeem luam tawm tag nrho cov ntaub ntawv lossis ib qho tshwj xeeb raws li, uas tsim nyog rau kev siv sib txawv.
Gait kev ntsuam xyuas
Lub software ntse soj ntsuam thiab hloov cov ntaub ntawv tseem ceeb rau hauv cov ntaub ntawv intuitive xws li lub voj voog mus, stride length, thiab stride zaus.
3D kho
Cov ntaub ntawv kaw tseg tuaj yeem rov ua dua arbitrarily hauv 3D kho hom, uas tuaj yeem siv los sib piv cov txiaj ntsig kev cob qhia tom qab kev cob qhia lossis rov ua qee cov ntaub ntawv.
Lub sijhawm ua haujlwm ntev
Lub gait tsom xam qhov system yog nruab nrog lub roj teeb muaj peev xwm loj, uas ua rau nws ua haujlwm tsis tu ncua rau 6 teev npog txog 80 tus neeg mob.
Motion capture capabilities muab submillimeter precision nyob rau hauv cov ntaub ntawv nyob rau hauv txoj hauj lwm cov ntaub ntawv, txoj kev duab, thiab cov ntaub ntawv hais txog kev coj cwj pwm rau cov kev tshawb fawb. Qhov no yog qhov tseem ceeb rau kev tshawb nrhiav ergonomics, suav nrog kev txheeb xyuas kev siv tau, kev ntsuas kev paub ntawm cov neeg siv, kev ntsuas kev nplij siab, thiab kev soj ntsuam tus neeg siv tus cwj pwm. Peb qhov kev daws teeb meem siab gait tsom qhov system tuaj yeem hloov kho kom haum rau qhov chaw sim ntawm ntau qhov ntau thiab tsawg.
Kev nce qib hauv cov thev naus laus zis tshiab tau ua rau muaj kev txhim kho ntawm cov cuab yeej siv thiab cov txheej txheem uas tso cai rau kev soj ntsuam lub hom phiaj, ua kom ntsuas tau zoo dua thiab ua tau zoo thiab muab cov kws tshaj lij nrog cov ntaub ntawv txhim khu kev qha. Ntau qhov kev tshawb fawb ua haujlwm ntau ntxiv qhia tau tias ntau yam tsis xws li precision, conformability, usability lossis transportability tau qhia tias cov tshuab nqa tau raws li lub cev sensors yog txoj hauv kev zoo rau kev tsom xam.
Cov nplais ib txwm siv los txheeb xyuas qhov kev daws teeb meem gait tsom xam qhov system tsis nyob hauv kev kho mob yog ib qho kev kawm, ua los ntawm cov kws kho mob tshwj xeeb uas saib xyuas qhov zoo ntawm tus neeg mob txoj kev mus los ntawm kev ua rau nws taug kev. Qhov no qee zaum ua raws li kev sojntsuam uas tus neeg mob tau hais kom muab qhov kev ntsuas ntawm qhov zoo ntawm nws txoj kev mus.
Piv txwv ntawm High Resolution Gait Analysis System Siv Scapular Plane raws li kev siv
Kev ntsuam xyuas kev ntsuas kev daws teeb meem siab gait tsom xam yog qhov feem ntau siv kev ntsuas kev ua haujlwm hauv cov kev tshawb fawb suav nrog hauv peb qhov kev tshuaj xyuas. High daws teeb meem gait tsom xam qhov system piav qhia txog kev hloov kinematic thiab kinetic pom hauv kev taug kev. Stride length, step width, GRF/contact intensity, stance, paw print area, thiab ceev yog qhov feem ntau tshaj tawm tsis. Txhua qhov ntsuas tau sawv cev sib txawv ntawm kev taug kev, tab sis tsuas yog qhov ntev ntawm txoj hlua thiab GRF / kev sib cuag tau ntseeg tau thiab tshwj xeeb pom tau los cuam tshuam txog kev hloov pauv ntawm lub xub pwg nyom tom qab RC kua muag lossis kho.
Txoj kev mus rau pem hauv ntej ntawm lub forelimb nyob rau hauv ib tug nas yuav ua tau zoo ib yam rau lub xub pwg abduction nyob rau hauv tib neeg thaum lub scapular dav hlau raug coj raws li ib tug siv. Stride length tau txhais raws li qhov kev ncua deb ntawm paw ntaus, uas sawv cev rau lub forelimb lub peev xwm rau active pem hauv ntej flexion. Cov txiaj ntsig no tau qhia tias RC leeg raug mob txo qis kev ua haujlwm rau pem hauv ntej flexion, thiab qhov kev raug mob cuam tshuam txog qhov ua haujlwm poob. Cov kev hloov pauv no kuj zoo ib yam li cov kev soj ntsuam soj ntsuam uas txo qis hauv ROM active feem ntau pom nyob rau hauv cov neeg mob uas loj heev RC kua muag dua nyob rau hauv cov neeg mob uas tsis loj heev kua muag. Qhov kev soj ntsuam no tau qhia tias qhov ntev stride tuaj yeem zoo li tib neeg kev kho mob los ntawm kev ua kom pom kev ua haujlwm ROM poob hauv RC cov qauv raug mob. Ntawm qhov tod tes, cov kauj ruam dav (qhov deb ntawm lub hauv ntej paws) feem ntau pom tsis cuam tshuam nyob rau hauv cov xwm txheej uas qhov ntev stride raug txo qis heev. Nws tau tawm tswv yim tias qhov dav dav ntawm kev ua haujlwm tsis zoo vim qhov qub forelimb hloov medially los txhawb lub cev hnyav dua, tsis yog tshwm sim los ntawm kev txwv ROM ntawm cov neeg raug mob forelimb. Yog li ntawd, nws yog tsim nyog los postulate tias cov kauj ruam dav yuav tsis yog ib tug txhim khu kev qha parameter rau kwv yees lub degree ntawm kev ua hauj lwm ntawm ib tug raug mob lub xub pwg nyom.
Vim lub zog yog lwm qhov tseem ceeb ntawm lub xub pwg nyom, cov kws tshawb fawb tau tsim ntau txoj hauv kev los ntsuas qhov tsis ncaj ntawm lub xub pwg nyom. Hauv cov nas, lub cev hnyav tau thauj khoom ntawm lub xub pwg pob qij txha thiab xa mus rau hauv av thaum taug kev, uas tau pab GRF los nthuav qhia lub peev xwm ntawm lub xub pwg nyom. Ib yam li ntawd, lub teeb siv hluav taws xob uas tau tsim nyob rau hauv ib qho kev ntsuas kev ua haujlwm siab tuaj yeem cuam tshuam lub peev xwm ntawm lub xub pwg vim tias lub teeb siv sib cuam tshuam zoo nrog GRF. Cov kws tshawb nrhiav tau siv lub teeb ci ntawm tus nas hneev taw los ntsuas nws lub xub pwg lub peev xwm thauj khoom.
Peb qhov kev tshawb fawb ntsuas qhov GRF / lub teeb siv, thiab lawv tau pom qhov txo qis hauv lub xub pwg loading peev xwm hauv RC tsim kua muag / kho qauv. Ib qho kev poob qis hauv GRF qhov tseem ceeb tau tshaj tawm yam tsis muaj kev hloov pauv ntawm lub sijhawm ntawm lub cev thiab qhov chaw gait tshwm sim hauv tus qauv nrog RC kua muag loj thiab kho qeeb. Raws li kev sib piv zoo ntawm GRF thiab qhov tsis sib xws ntawm lub cev thiab qhov chaw, GRF tau lees paub tias yog qhov ntsuas qhov ntsuas siab tshaj plaws los qhia qhov cuam tshuam ntawm lub xub pwg nyom. Ntxiv mus, qhov txo qis hauv kev thauj khoom muaj peev xwm cuam tshuam nrog tib neeg cov txiaj ntsig kev kho mob uas qhia cov neeg mob poob 60-70% ntawm lawv lub xub pwg nyom tom qab RC kua muag. Yog li, GRF thiab lub teeb siv lub teeb yog txhim khu kev qha thiab cov neeg sawv cev tsis tuaj yeem siv los nthuav qhia lub xub pwg loading peev xwm hauv RC raug mob qauv.
Kev mob yog lwm qhov tseem ceeb uas hloov kho qhov ua tau zoo, thiab kev kho mob, qhov mob tau qhia los ntawm cov neeg mob. Txawm hais tias qhov mob tsis tuaj yeem ntsuas ncaj qha hauv kev tshawb fawb tsiaj, nws tuaj yeem cuam tshuam txog kev hloov pauv hauv kev taug kev. Qhov cuam tshuam ntawm qhov mob ntawm lub xub pwg nyom tau txwv rau thawj plaub hnub tom qab phais.
Tsiaj Treadmill Gait Analysis System
Ib qho inertial ntsuas ntsuas raws li canine gait tsom xam qhov system. Txhawm rau tshawb xyuas qhov tseeb ntawm cov algorithms, cov tsiaj tau taug kev ntawm lub treadmill thiab ntsuas ib txhij nrog IMU system, lub kaw lus kho qhov muag thiab ob lub koob yees duab. Qhov ntau yam ntawm kev kwv yees tau muab piv rau cov tshuab kho qhov muag, nrog rau tag nrho cov kauj ruam kaw. Txhawm rau ntsuam xyuas qhov stance thiab viav vias theem nrhiav pom, tag nrho cov kauj ruam tau muab teev tseg rau hauv cov ntaub ntawv kaw tseg thiab muab piv nrog cov zis ntawm cov algorithm.
Qhov zoo ntawm Tsiaj Treadmill Gait Analysis System
Kev tsom xam kom muaj nuj nqis
Lub kaw lus tso cai rau kev ntsuas qhov tseeb thiab qhov ntau ntawm ntau yam kev taug kev xws li qhov ntev ntawm txoj hlua, kauj ruam zaus, paw tso, thiab gait symmetry.
Standardized xeem
Los ntawm kev siv lub treadmill, cov kws tshawb fawb tuaj yeem tswj tau qhov nrawm, qhov siab, thiab lub sijhawm ntawm qhov kev tawm dag zog, kom ntseeg tau cov qauv kev sim ntsuas thoob plaws cov kev sim sib txawv thiab cov ncauj lus.
Kev kawm coj cwj pwm
Ntxiv nrog rau kev tsom xam gait, lub tshuab treadmill tuaj yeem siv los kawm lwm yam ntawm tus cwj pwm tsiaj, xws li kev tawm dag zog, kev ua siab ntev, kev sib koom ua ke ntawm lub cev muaj zog, thiab cov lus teb rau stimuli.
Data visualization thiab tsom xam
Lub kaw lus feem ntau suav nrog software rau lub sijhawm tiag tiag cov ntaub ntawv pom, tsom xam, thiab khaws cia. Cov kws tshawb fawb tau yooj yim txheeb xyuas cov ntaub ntawv khaws tseg, tsim cov duab kos, thiab tshem tawm cov kev pom muaj txiaj ntsig los txhawb lawv cov kev tshawb fawb tshawb pom.
Nrov Daim Ntawv Thov ntawm Tsiaj Treadmill Gait Analysis System hauv Veterinary Community
Theanimal treadmill gait tsom xam qhov system nyob rau hauv thaj chaw ntawm biomechanical gait tsom mus rau lub ntiaj teb no ntawm veterinary tshuaj. Kev kuaj mob tag nrho ntawm cov dev 'gait tuaj yeem ua tiav yam tsis muaj kev npaj ntxiv. Qhov yooj yim-rau-ua haujlwm PC tsom xam software muab scientifically suab thiab siv tsis tau gait - tom qab tsis siv neeg los yog phau ntawv raws li-kos npe ntawm lub caj dab.Tus tsiaj treadmill gait tsom xam system muaj ib tug treadmill los yog platform nruab nrog acalibrated siab sensor matrix thiab ib los yog ob peb. synchronized koob yees duab.
Cov kab mob hauv cov dev, xws li cov uas yuav tshwm sim vim muaj kev hloov pauv lossis raug mob rau lub cev musculoskeletal, raug tshuaj xyuas kom raug thiab tso cai rau kev kho mob hauv txhua hnub. Cov tsiaj treadmill gait tsom xam qhov system qhia txog kev ua haujlwm tsis txaus uas nyuaj rau kev kuaj pom ntawm qhov muag liab qab, yog li tso cai rau kev kuaj mob ntxov ntawm incipient lameness.
Cov tsiaj treadmill gait tsom xam qhov system qhia nthuav tawm cov kev sib tiv tauj thiab cov qauv kev sib txuas ntawm txhua lub paw overlayed nrog cov kab dov uas qhia txog txoj hauv kev ntawm nws qhov chaw siab thaum lub zog txav. Cov gait parameters (cov kauj ruam lengths, ntev ntawm lub voj voog gait, ceev, cadence, stance thiab viav vias theem faib) yog nthuav tawm nyob rau hauv ib tug yooj yim-readable rooj nrog cov zauv muaj nuj nqis thiab bar graphs.Cov chav kawm ntawm lub cev qhov chaw ntawm lub ntiajteb txawj nqus yields muaj nuj nqis. cov ntaub ntawv hais txog symmetry thiab stability ntawm gait. Daim ntawv tshaj tawm muab ib txoj hauv kev yooj yim kom pom hom kev taug kev los ntawm kev qhia qhov kev sib cuag quab yuam rau txhua ceg, thiab daim duab ntoo khaub lig nrog cov qauv footfall. Daim ntawv tshaj tawm tuaj yeem sib piv cov txiaj ntsig kev tshuaj ntsuam ntawm ob cov ntaub ntawv kom yooj yim saib xyuas cov txiaj ntsig kev kho mob.
Qhia ntxaws ntxaws txog Kev Tshawb Fawb Txog Tsiaj Treadmill Gait Analysis System ntawm Tsiaj
Kev nce qib hauv kev raug mob txha caj qaum (SCI) kev tshawb fawb yog nyob ntawm cov qauv tsiaj zoo, uas nyob rau hauv lem cia siab rau cov txiaj ntsig tau zoo tuaj yeem txheeb xyuas qhov sib txawv ntawm cov tsiaj tom qab raug mob. Txog rau tam sim no, feem ntau kev ntsuas ntawm kev ua haujlwm tsis zoo tom qab SCI tso siab rau qhov kev ntsuas ntawm cov neeg soj ntsuam lossis qhov qeeb ntawm kev ntsuas kev ntsuas kev taw qhia.
Txoj kev tshawb fawb tam sim no sib piv cov gait ntawm ib txwm thiab cov nas raug mob uas siv Tsiaj treadmill gait tsom xam qhov system. siv lub pob tshab treadmill siv thiab lub koob yees duab ceev ceev los ntes cov hneev taw ntawm cov tsiaj thiab cia li txheeb xyuas cov yam ntxwv ntawm kev mus. Cov neeg laus poj niam nas tau qhia rau lub treadmill ua ntej tau txais ib qho qauv me me, nruab nrab, lossis sham contusion txha caj qaum raug mob. Tsiaj treadmill gait analysis system gait tsom xam tau ua txhua lub lim tiam rau 10 lub lis piam thiab piv nrog cov qhab nia ntawm basso nas nplai. Cov txiaj ntsig tau qhia tias qhov software no tau ua tiav qhov sib txawv ntawm cov tsiaj sham los ntawm cov tsiaj raug mob ntawm ntau tus yam ntxwv gait, nrog rau hindlimb viav vias lub sij hawm, stride ntev, ntiv taw kis, thiab khiav dav. Qhov sib txawv tau pom ntawm qhov mob me me thiab nruab nrab contusion, qhia tau hais tias muaj kev nkag siab zoo hauv lub cev. Tsheb khiav dav, ib qho kev ntsuas ntawm tus tsiaj lub hindlimb puag ntawm kev txhawb nqa, correlated ob leeg nrog spared dawb teeb meem feem pua thiab nrog davhlau ya nyob twg. Tsiaj treadmill gait tsom xam qhov system tso cai rau lub hom phiaj thiab ceev tus cwj pwm kev soj ntsuam ntawm locomotor muaj nuj nqi tom qab me me-nruab nrab contusive SCI, qhov twg cov nas feem ntau tseem pom hindlimb qhov hnyav txhawb nqa thiab cog paj paw thaum taug kev.
Lub Hom Phiaj Tsiaj Treadmill Gait Analysis System muab cov ntaub ntawv kho mob ntseeg tau
Kev tsom xam ntawm lub hom phiaj tuaj yeem muab cov kws kho mob nrog cov ntaub ntawv tseem ceeb rau kev txiav txim siab kho mob. Nws tuaj yeem siv tsis tsuas yog siv rau kom muaj nuj nqis thiab sib txawv gait rau kev kuaj mob, tab sis kuj tseem yuav soj ntsuam kev kho kom rov zoo thiab kho kom rov zoo. Tsis tas li ntawd, cov ntaub ntawv tseem ceeb uas tau sau tseg tuaj yeem muab cov ntaub ntawv tseem ceeb rau kev txiav txim siab yug me nyuam.
Tsiaj treadmill gait tsom xam tshuab tam sim no siv nyob rau hauv veterinary tshuaj los sau kinematic thiab kinetic cov ntaub ntawv yog lub koob yees duab raws li systems, quab yuam phaj systems, accelerometer-based systems, nto electromyography ntsuas tshuab los yog instrumented treadmills. Lub koob yees duab-raws li cov tshuab uas taug qab kho qhov muag, ua haujlwm, lossis cov cim cim txuas nrog rau tus dev lub cev yog feem ntau siv hauv cov chaw tshawb fawb tab sis tsis tshua muaj nyob hauv cov chaw kho tsiaj vim tias lawv kim heev thiab xav tau qhov chaw tshwj xeeb los teeb tsa lub kaw lus. Kev ntsuas qhov ntsuas hauv av, xws li cov phiaj xwm quab yuam, tau pom tias yog cov cim qhia tseeb ntawm cov qauv gait tsis zoo lossis lameness, tshwj xeeb tshaj yog thaum ua ke nrog lub koob yees duab raws li cov khoom siv taug qab, tab sis xav tau lub sijhawm ntev acclimatization thiab kev cob qhia tus dev mus rau kev taug kev. nto.
Ntau cov kev tshawb fawb qhia tau hais tias inertial ntsuas chav tsev muab cov ntaub ntawv tseem ceeb rau kev tsom xam ntawm canine gait . Nyob rau hauv ib txoj kev tshawb no lub ncov ntsug rog (PVF) ntsuas nrog ib tug quab yuam platform tau muab piv nrog rau kev ntsuas los ntawm ib tug triaxial accelerometer muab tso rau dorsally nyob rau hauv lub thoracic los yog lumbar cheeb tsam. Muaj kev pom zoo zoo thiab tseem ceeb ntawm PVF ntawm lub accelerometer thiab lub zog platform rau lub forelimbs thiab qhov zoo thiab tsis pom zoo rau cov hindlimbs. piav qhia txog kev siv thiab kev ntseeg siab ntawm accelerometers hauv kev ntsuam xyuas kev noj qab haus huv ntawm cov dev thiab dev nrog kev kuaj mob ntawm cov leeg nqaij dystrophy. Nws tau tshaj tawm tias kinematics kaw nrog lub ntsuas inertial ntsuas (IMU) hauv lub dav hlau sagittal hauv dev, pom muaj kev sib raug zoo nrog optically kaw kinematics, yog li kev siv IMU sensors tuaj yeem muab lwm txoj hauv kev kho qhov muag kinematic gait tsom xam thaum tso cai khaws cov ntaub ntawv sab nraud ntawm chav kuaj. . Nws tau nthuav tawm IMU sensor-raws li kev ntsuas kev ntsuas rau cov dev uas pom tau tias muaj kev nkag siab zoo thiab rov ua dua nrog qhov tseeb yuav txaus los kuaj xyuas cov kev kho mob cuam tshuam txog kev txawv txav hauv cov dev. Lawv xaus lus tias, nrog rau kev txhim kho ntxiv, lub kaw lus tuaj yeem muaj ntau yam kev siv hauv kev tshawb fawb thiab kev kho mob.
Mouse Vestibular Ocular Reflex Testing System
Kev nce qib tau ua rau nws muaj peev xwm ntsuas qhov muag qhov muag ntawm nas vestibular ocular reflex testing system, yog li tam sim no nws muaj peev xwm siv lub zog tshawb nrhiav ntawm qhov muag txav cov ntaub ntawv los ua tus cwj pwm tsis zoo ntawm lub paj hlwb hauv kev hloov pauv caj ces. Cov cuab yeej tshuaj ntsuam xyuas siv hauv kev tshawb fawb ocular lub cev muaj zog thiab ua kom pom lawv lub peev xwm los nthuav tawm cov teeb meem ntawm kev pom kev, pob ntseg sab hauv, thiab cerebellum. Kev tshuaj xyuas qhov muag txav yog ib feem tseem ceeb ntawm kev ntsuam xyuas neurological; kev faib tawm ntawm neural circuits uas tswj cov kev txav no yog qhov uas lawv cuam tshuam - feem ntau hauv cov yam ntxwv zoo heev - los ntawm ntau cov txheej txheem kab mob.
Qhov zoo ntawm Mouse Vestibular Ocular Reflex Testing System
Vestibular stimulations thiab nrhiav tau cov ntaub ntawv
Cov cim qhov muag thiab lub taub hau txoj hauj lwm tau raug coj mus kuaj, digitally kaw nyob rau hauv spike ib puag ncig thiab tom qab ntawd xa mus rau hauv lub programming ib puag ncig rau kev soj ntsuam off-line.
Cov ntaub ntawv tsom xam
Cov txheej txheem tshuaj ntsuam rau kab rov tav angular vestibulo-ocular reflex twb tau tshaj tawm rau lwm qhov. Luv luv, kab rov tav thiab ntsug qhov muag thiab lub taub hau txav cov ntaub ntawv tau digitally tsawg dhau-filtered, thiab cov ntaub ntawv txoj hauj lwm tau sib txawv kom tau txais cov kab nrawm. Ntu ntawm cov ntaub ntawv nrog saccades raug cais tawm los ntawm kev txheeb xyuas.
Kev txheeb cais
Kev ua tiav ntawm tag nrho cov txiaj ntsig tau ua tiav siv software. Kev sib piv tswj tau ua tiav cais siv tib txoj kev.
High precision
Lub kaw lus tso cai rau kev ntsuas qhov tseeb thiab kev tshuaj xyuas ntawm vestibular ocular reflex (VOR) cov lus teb hauv cov nas, muab cov ntaub ntawv tseeb ntawm qhov muag txav hauv kev cuam tshuam nrog lub taub hau txav. Qhov no high precision yog qhov tseem ceeb rau kev kawm vestibular muaj nuj nqi.
Lub vestibulo-ocular reflex (VOR) thiab optokinetic reflex (OKR) ua haujlwm sib koom ua ke kom ruaj khov ntsia hauv teb rau lub taub hau txav. Peb yav dhau los tau ua pov thawj tias 14-hnub visuo-vestibular mismatch (VVM) raws tu qauv siv rau hauv cov nas coj tus cwj pwm ywj pheej txo qhov VOR nce. Ntawm no, peb qhia thawj zaug tias OKR nce kuj raug txo thiab tshaj tawm txog kev rov qab los ntawm VOR thiab OKR tom qab kawg ntawm VVM raws tu qauv.
Siv sinusoidally-modulated stimulations, qhov txo qis hauv VOR thiab OKR tau pom tias yog qhov kev xaiv ntau zaus nrog kev txo qis rau ntau zaus.< 0.5 Hz. Constant-velocity OKR stimulation tests demonstrated that the persistent components of the OKR were not modified while the transient, initial responses were. To identify the signals driving VOR and OKR reductions, we compared the responses of mice exposed to a high-contrast and no-contrast VVM. Despite being more robust in the high-contrast conditions, reductions were largely comparable and recovered with a similar time course. An analysis that directly compared VOR and OKR responses revealed that, alterations in the VOR were of significantly larger amplitude with significantly slower dynamics of recovery. Our findings are evidence for a frequency-selective influence of visual signals in the tuning of gaze stabilizing reflexes in normal mice.
Nyob rau hauv lub neej txhua hnub, lub taub hau ntuj txav hauv cov tsiaj nyeg npog ntau qhov ntau zaus thiab nrawm. Txhawm rau kom tsis txhob pom qhov muag tsis pom kev, cov duab txav ntawm lub retina raug txo qis los ntawm kev siv qhov muag pom. Cov qhov muag-hauv-qhov chaw txav no yog hu ua gaze stabilization qhov muag txav, uas tshwm sim los ntawm kev hloov pauv ntawm kev hnov mob rau hauv cov lus txib ntawm lub cev muaj zog. Vertebrates muaj ob lub ntsej muag stabilizing reflexes - lub optokinetic reflex (OKR) thiab lub vestibulo-ocular reflex (VOR) - uas ua synergistically los them rau ib puag ncig thiab kev txav ntawm tus kheej. Cov lus teb OKR vam khom rau cov kev taw qhia-xaiv cov hlwb retinal ganglion uas ua tau zoo rau cov kev txav qeeb ntawm qhov pom kev pom (± 3º / s hauv nas). Yog li ntawd, OKR nce yog inversely proportional rau qhov ceev ntawm qhov pom kev stimulus.
Ntawm qhov tod tes, vestibular acceleration-sensitive neurons lub luag hauj lwm rau VOR yog rhiab heev rau nruab nrab-rau-siab ntau zaus lub taub hau motions8. Tsis tas li ntawd, OKR tuaj yeem teb rau qhov tsis tu ncua-ceev pom kev taw qhia thaum lub vestibular system encodes tsuas yog tsis tas li, lub taub hau nrawm nrawm. Cov optokinetic thiab vestibulo-ocular reflexes yog li ua haujlwm ntxiv, lawv cov kev sib xyaw ua ke ua kom muaj txiaj ntsig zoo saib thiab tso cai rau kev ntxub ntxaug tus kheej tsim los ntawm kev tawm tsam sab nraud hauv cov xwm txheej feem ntau ntsib.
Lub VOR ua haujlwm raws li lub kaw lus qhib: nws ua haujlwm tag nrho hauv qhov tsaus ntuj, piv txwv li, lub pob ntseg sab hauv vestibular teeb liab tsim kom them nyiaj qhov muag txav txawm tias tsis muaj kev tawm tswv yim pom. Hauv cov nas tsuag, qhov kev txhim kho thawj zaug ntawm VOR tso siab rau qhov kev loj hlob ntxov ntawm vestibular circuitry txawm tias ua ntej qhib qhov muag. Txawm li cas los xij, kev pom kev pom yog qhov tseem ceeb rau kev txhim kho thiab kev ua haujlwm zoo ntawm VOR: nws qhov kev kho kom zoo yog nyob ntawm qhov pom kev tawm tswv yim uas qhia txog qhov ua tau zoo ntawm qhov kev them nyiaj qhov muag. Thaum tsis pom kev, xws li nyob rau hauv congenitally los yog adventitiously dig muag, VOR yog impaired. Qhov nce ntawm vestibulo-ocular reflex txhim kho tom qab qhib qhov muag hauv nas, thaum lub sij hawm hloov mus rau theem me me. Tsis tas li ntawd, lub zeem muag cuam tshuam rau lub sijhawm tsis tu ncua ntawm qhov ceev ceev cia16, kev txhim kho ntawm vestibular nuclei neurons thiab nrhiav tau ntawm lawv cov khoom yas.
Peb lub Hoobkas
Guangzhou G-Cell Technology Co., Ltd. yog lub tuam txhab thev naus laus zis tshiab tsim los ntawm kev cia siab rau Tsinghua University Shenzhen Kawm Tiav Tsev Kawm Ntawv, Southern University of Science thiab Technology, thiab South China Normal University, thiab peb tsom mus rau daim ntawv thov ntawm optical imaging technology nyob rau hauv lub teb ntawm life sciences. Rau cov chav nyob hauv cov lus qhia txog kev thov, peb tuaj yeem muab koj cov khoom siv kho qhov muag pom kev thiab cov kev daws teeb meem. Peb muaj qhov ua tiav kev sim kho qhov muag qhov chaw sim thiab ib pawg ntawm cov tub ntxhais hluas cov pob txha zoo. Raws li kev sib koom ua ke ntawm cov khoom siv hauv chav kuaj thiab kev lag luam hauv Is Taws Nem, lub tuam txhab tau cog lus los tsim lub cim tshiab ntawm cov khoom siv ntse ntse.
FAQ
Peb nyob nraum kev soj ntsuam tsiaj tus cwj pwm manufacturers thiab lwm tus neeg nyob hauv Suav teb, tshwj xeeb hauv kev muab cov khoom zoo nrog tus nqi qis. Peb sov siab txais tos koj mus yuav customized tsiaj kev tsom xam ua nyob rau hauv Suav teb nov los ntawm peb lub tuam txhab. Tiv tauj peb rau kev hais lus.